(cont'd from yesterday's post)
Irreversibly damaged cells that somehow escape normal self-destruct mechanisms continue to build up and cause health problems over the years. Oisin Biotechnologies explains it:
"When cells detect that they have been irreversibly damaged, they enter a non-dividing condition [called] senescence . . . Ideally, they should die by the process known as apoptosis, but as we age, more and more frequently they don’t. They become zombie cells – unable to kill themselves or resume normal function.
"Senescent cells secrete molecules that cause inflammation in an effort to attract immune cells that would usually clear them. But for reasons that are not fully known, as we age, persistently senescent cells accumulate, leading to a vast number of age-related diseases."
So their goal is to improve health and lifespan by targeting senescent cells and destroying them. "Significant" success was achieved, so far, in the testing of their therapy on aged mice.
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